2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7926S
    Pentadecane-d32
    		Inhibitor 99.2%
    Pentadecane-d32 is the deuterium labeled Pentadecane (HY-N7926). Pentadecane is an orally active natural plant volatile alkane with anti-inflammatory, analgesic, antipyretic and anti-leishmanial activities. Pentadecane presents IC50 values of 65.3 μM, 60.5 μM and 194.8 μM against Leishmania infantum promastigotes, amastigotes and intracellular amastigotes, respectively. Pentadecane downregulates the mRNA expression of TNF-α and IL-12 and inhibits the release of inflammatory mediators. Pentadecane arrests the cell cycle of Leishmania infantum and induces apoptosis. Pentadecane can be applied to the research of inflammation and leishmaniasis.
    Pentadecane-d<sub>32</sub>
  • HY-W009109
    Antimalarial agent 1
    		Inhibitor 98.57%
    Antimalarial agent 1 is a potent antimalarial agent.
    Antimalarial agent 1
  • HY-128421R
    Tridecanedioic acid (Standard)
    		Inhibitor
    Tridecanedioic acid (Standard) is the analytical standard of Tridecanedioic acid (HY-128421). This product is intended for research and analytical applications. Tridecanedioic acid is an endogenous metabolite. Tridecanedioic acid is an endogenous metabolite. Tridecanedioic acid is related to the metabolic regulation of non-alcoholic fatty liver disease (NASH) and may be an important node molecule in the intestinal microbiota-host metabolism interaction network. Tridecanedioic acid is significantly accumulated in tolerant cabbage-type rapeseed varieties and has a lower content in sensitive varieties. It plays an important role in the defense response against the infection of the small cabbage moth (Plutella xylostella). Tridecanedioic acid can be used as a biomarker for plant insect resistance or a diagnostic marker for metabolic diseases.
    Tridecanedioic acid (Standard)
  • HY-13557R
    Ascomycin (Standard)
    		Inhibitor
    Ascomycin (Standard) is the analytical standard of Ascomycin. This product is intended for research and analytical applications. Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research[1][2].
    Ascomycin (Standard)
  • HY-135810
    Cletoquine
    		Inhibitor
    Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment.
    Cletoquine
  • HY-103033
    T.cruzi-IN-1
    		Inhibitor 99.11%
    T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease.
    T.cruzi-IN-1
  • HY-B1327A
    Chlortetracycline
    		Inhibitor
    Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline
  • HY-P3361
    IDR-1018
    		Inhibitor
    IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate).
    IDR-1018
  • HY-P4836
    LL-37 FK-13
    		Inhibitor
    LL-37 FK-13 is an antimicrobial agent, that inhibits Trichomonas vaginalis. LL-37 FK-13 exhibits slight hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts.
    LL-37 FK-13
  • HY-W071746R
    Linolelaidic acid (Standard)
    		Inhibitor
    Linolelaidic acid (Standard) is the analytical standard of Linolelaidic acid. This product is intended for research and analytical applications. Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections[1][2][3].
    Linolelaidic acid (Standard)
  • HY-175741
    IID432
    		Inhibitor 98.20%
    IID432 is a Trypanosoma cruzi Topoisomerase II inhibitor with an EC50 of 8  nM for Trypanosoma cruzi. IID432, a single dose of 25 mg/kg, can achieve relapse-free parasite clearance in mouse models of chronic Chagas disease. IID432 can be used for Chagas disease research.
    IID432
  • HY-111757
    ABBV-4083
    		Inhibitor
    ABBV-4083 is an analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.
    ABBV-4083
  • HY-117179
    Endosulfan sulfate
    		Inhibitor 99.94%
    Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan.
    Endosulfan sulfate
  • HY-B0439S1
    Sulfadoxine-d3
    		Inhibitor 98.0%
    Sulfadoxine-d3 is a deuterium labeled Sulfadoxine (HY-B0439). Sulfadoxine is a sulfonamide that is used, usually in combination with Pyrimethamine(HY-18062), for multidrug-resistant Plasmodium falciparum and P. vivax inhibition. Unlike PYR, Sulfadoxine has no impact on HIV replication or MT-2 cell cycle progression. But also Sulfadoxine exhibits suppression on respiratory, and urinary tract infections.
    Sulfadoxine-d<sub>3</sub>
  • HY-103353A
    SID 26681509 quarterhydrate
    		Inhibitor 98.02%
    SID 26681509 quarterhydrate is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC50 of 56 nM. SID 26681509 quarterhydrate inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC50s of 15.4 μM and 12.5 μM, respectively. SID 26681509 quarterhydrate shows no inhibitory activity against cathepsin G.
    SID 26681509 quarterhydrate
  • HY-136240
    Tioxazafen
    		Inhibitor
    Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton.
    Tioxazafen
  • HY-B1072A
    D-Phenothrin
    		Inhibitor
    D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops.
    D-Phenothrin
  • HY-138502A
    Melarsomine dihydrochloride
    		Inhibitor
    Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections.
    Melarsomine dihydrochloride
  • HY-N6674
    Diazepinomicin
    		Inhibitor 98.04%
    Diazepinomicin (ECO-4601) is an anticancer and antibacterial agent. Diazepinomicin can be produced by a Micromonospora strain. Diazepinomicin induces Apoptosis. Diazepinomicin inhibits the proteases Rhodesain and Cathepsin L at an IC50 of 70-90 μM. Diazepinomicin possesses anti-inflammatory and anti-tumor activity. Diazepinomicin has demonstrated activity against hepatocellular carcinoma. Diazepinomicin shows antiparasitic activity against trypomastigote forms of Trypanosoma brucei with an IC50 of 13.5 μM. Diazepinomicin exhibits moderate antibacterial activity against specific Gram-positive bacteria, with an MIC of approximately 32 μg/mL.
    Diazepinomicin
  • HY-B0223S
    Albendazole-d3
    		Inhibitor 98.28%
    Albendazole-d3 is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations.
    Albendazole-d<sub>3</sub>
Parasite Isoform Comparison

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